(MedPage Today) -- Two new immunotherapy-chemotherapy options are now approved for patients with primary advanced or recurrent endometrial cancer, the FDA announced.
On Monday, the agency approved the PD-1-directed immune checkpoint inhibitor...
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-
Two New Immunotherapy-Chemo Options Approved for Endometrial Cancer
via medpagetoday.com -
A Multivitamin a Day Won't Keep Death Away
via medpagetoday.com(MedPage Today) -- Taking a multivitamin every day for many years didn't cut the risk of death in an analysis of three prospective cohort studies that involved more than 20 years of follow-up.
Daily multivitamin use was actually associated with... -
More Evidence That Flu Is Linked to Heart Attacks
via medpagetoday.com(MedPage Today) -- Influenza infection was associated with an increased risk of acute myocardial infarction (MI), especially for those without a prior hospitalization for coronary artery disease (CAD), according to a Dutch observational case series... -
In CROWN, Lorlatinib Shows Longest PFS in ALK-Positive Lung Cancer
via medpagetoday.com(MedPage Today) -- In 5-year follow-up data from the phase III CROWN trial of ALK-positive advanced non-small cell lung cancer (NSCLC), patients receiving lorlatinib (Lorbrena) had the longest progression-free survival (PFS) ever reported in this... -
TNBC: Distinct Tumor Immune Microenvironments at Metastatic Sites
via medpagetoday.com(MedPage Today) -- A study presented at the American Society of Clinical Oncology annual meeting examined the tumor immune microenvironments of triple-negative breast cancer (TNBC) at the primary and metastatic sites to investigate how the immune... -
Nationwide Coffee Recall; Aspirin Misuse Common; Gena Rowlands' Alzheimer's Disease
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
Snapchill recalled all of its canned coffee products distributed nationwide through coffee roasters and retailers due to potential botulinum toxin contamination... -
CDC Assists in Study Testing for Asymptomatic Bird Flu in Humans
via medpagetoday.com(MedPage Today) -- Top brass at the CDC, the National Institutes of Health (NIH), and other agencies shared a roadmap for preventing and understanding human infection with bird flu, along with their plan for developing countermeasures against the... -
A Call to Action on Gestational Diabetes
via medpagetoday.com(MedPage Today) -- ORLANDO--Earlier screening and treatment for gestational diabetes, as well as a "shift to a holistic life-course approach," are needed to reduce the toll it takes on women.
That was the conclusion of a series of papers published... -
Surprisingly High Hypercortisolism Prevalence With Uncontrolled Type 2 Diabetes
via medpagetoday.com(MedPage Today) -- ORLANDO--A surprisingly high prevalence of hypercortisolism was found in people with uncontrolled diabetes, according to the two-part, phase IV CATALYST study.
Of 1,055 patients with difficult-to-treat type 2 diabetes, 24... -
CDC Tells Docs to Be Alert for Dengue as Cases Ramp Up Worldwide
via medpagetoday.com(MedPage Today) -- The CDC on Tuesday warned doctors to be alert for dengue cases as the tropical disease breaks international records.
The virus, which is spread by mosquitoes, has been surging worldwide, helped by climate change. In barely 6... -
What Should Be Done About Long-Term Care?
via medpagetoday.com(MedPage Today) -- The problem of how to pay for long-term care continues to bedevil policy experts, with some arguing for a combination public-private insurance market and others arguing that a social insurance program is the best solution.
Marc... -
Lung Transplant Graft Outcomes Relate Back to Donor Care Setting
via medpagetoday.com(MedPage Today) -- Surprisingly, there was a difference in graft survival between lungs recovered from hospital-based donor care units (DCUs) and those recovered from independent DCUs, according to an analysis of national Organ Procurement and... -
Dermatologist Debunks Sunscreen Misinformation Making the Rounds on Social Media
via medpagetoday.com(MedPage Today) -- Welcome to Culture Clinic, MedPage Today's collaboration with Northwell Health to offer a healthcare professional's take on the latest viral medical topics.
As summer temperatures heat up, so have social media posts spreading... -
Temsirolimus Plus Chemotherapy Fails in Rare Childhood Cancer
via medpagetoday.com(MedPage Today) -- Adding the mTOR inhibitor temsirolimus (Torisel) to chemotherapy in the first-line setting failed to improve event-free survival (EFS) among young patients with intermediate-risk rhabdomyosarcoma, a phase III trial from the Children... -
Blood Panel Predicts Parkinson's; Transgender Neurologic Care; Rare COVID Case
via medpagetoday.com(MedPage Today) -- A blood panel predicted Parkinson's disease up to 7 years before symptom onset. (Nature Communications)
Homozygosity for R47H in the TREM2 gene substantially raised the risk of Alzheimer's disease. (New England Journal of Medicine... -
Low-Dose SGLT2 Inhibitor May Protect Kidneys in Youth With T1D
via medpagetoday.com(MedPage Today) -- ORLANDO--Adding a low dose of an SGLT2 inhibitor to insulin improved renal function and glycemic control in adolescents with type 1 diabetes (T1D), the late-breaking ATTEMPT trial found.
In the 98-patient study, treatment... -
RNAi Win in ATTR-CM; HF Congestion Monitor Approved; Lp(a) & In-Stent Restenosis
via medpagetoday.com(MedPage Today) -- Vutrisiran (Amvuttra), an RNA-interfering (RNAi) therapy, reduced hard events and disease progression in transthyretin amyloidosis cardiomyopathy (ATTR-CM) regardless of background tafamidis (Vyndamax, Vyndaqel) therapy, according... -
What's Driving Avian Influenza Virus Evolution? Human Food Systems
via medpagetoday.com(MedPage Today) -- The noble push to achieve "Freedom from Hunger" gained momentum after World War II with the formation of the Food and Agriculture Organization of the United Nations, which "strives to eradicate hunger, food insecurity and all... -
In-Hospital Continuous Glucose Monitoring Can't Budge T2D Control
via medpagetoday.com(MedPage Today) -- ORLANDO--Use of continuous glucose monitors didn't make much difference in achieving tight glucose control for hospitalized type 2 diabetes patients, the TIGHT trial showed.
Patients randomized to an intensive control target... -
First GLP-1 Generic Launched; 5:2 Intermittent Fasting Win; WHO's Ozempic Warning
via medpagetoday.com(MedPage Today) -- Teva Pharmaceuticals announced the launch of the first authorized GLP-1 receptor agonist generic of liraglutide 1.8 mg injection (Victoza) in the U.S.
Combining 3-mg liraglutide (Saxenda) with exercise yielded more weight loss... -
Preeclampsia Can Be Fatal. New Blood Tests Aim to Determine Who Is at Risk.
via medpagetoday.com(MedPage Today) -- When patients are expecting a baby, they hope nothing goes wrong. But at least one in 20 people who are pregnant develop preeclampsia, a high blood pressure disorder that kills 70,000 women and 500,000 babies worldwide every... -
Real-World Analysis Identifies Meds Tied to Higher Risk of Liver Injury
via medpagetoday.com(MedPage Today) -- Real-world data can be used to identify the most potentially hepatotoxic medications based on incidence rates of severe acute liver injury among patients without pre-existing liver or biliary disease, according to a series of... -
State Sues Two PBMs, Accusing Them of Fueling Opioid Epidemic
via medpagetoday.com(MedPage Today) -- Arkansas on Monday sued two pharmacy benefit managers (PBMs) that oversee coverage for insurers, employers, and other large clients, accusing them of fueling the opioid crisis in the state.
Attorney General Tim Griffin (R) filed... -
Combo of Approved Agents Active in High-Risk Large B-Cell Lymphoma
via medpagetoday.com(MedPage Today) -- A subgroup analysis of a phase Ib/II trial showed durable responses with mosunetuzumab (Lunsumio) plus polatuzumab vedotin (Polivy) in transplant-ineligible large B-cell lymphoma patients in early relapse or with primary refractory... -
The Power of 'Enough-ness' in Medicine
via medpagetoday.com(MedPage Today) -- My son, his wife, and their 3-year-old son recently made the long trans-Atlantic flight from their home in Honolulu to our "summer" home in Asheville, North Carolina, a lovely town situated in the foothills of the Blue Ridge... -
Cardiovascular Risks Established in Childhood Don't Just Go Away
via medpagetoday.com(MedPage Today) -- People showed lingering long-term effects of childhood cardiovascular risk factors no matter the changes in adulthood, a population-level cohort study found.
Various childhood risk factors were associated with adult cardiovascular... -
What Are the Available Treatments for Non-Clear Cell Kidney Cancer?
via medpagetoday.com(MedPage Today) -- In this exclusive MedPage Today video, Sumanta "Monty" K. Pal, MD, of City of Hope in Duarte, California, discusses some of the high points of his presentation at the recent American Society of Clinical Oncology (ASCO) meeting... -
Ice Cream Recall; COVID Summer Wave; Gun Violence a Public Health Crisis
via medpagetoday.com(MedPage Today) -- Note that some links may require registration or subscription.
Totally Cool is recalling multiple brands of ice cream products because they have the potential to be contaminated with Listeria monocytogenes.
With COVID cases... -
Docs in Abortion Ban States Find Workarounds to Deliver Care
via medpagetoday.com(MedPage Today) -- Two years ago, the Dobbs v. Jackson Women's Health Organization decision overturned Roe v. Wade, upending federal abortion protections and making abortion access and training a patchwork. Despite new challenges, ob/gyns practicing... -
Major Heart Events Down With Metabolic Surgery for Apnea Patients With Obesity
via medpagetoday.com(MedPage Today) -- Metabolic surgery became the first therapy associated with a reduction in incident cardiovascular disease and death among patients with obesity and obstructive sleep apnea (OSA), based on a retrospective cohort study.
Such patients...
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